Oscar-winning director Jonathan Demme died on Wednesday of esophageal cancer complications. He was 73 years old. The filmmaker is best known for directing the 1991 thriller 'The Silence of the Lambs." The movie earned a Best Picture Oscar, along with Academy Awards for stars Jodie Foster, Anthony Hopkins and Demme himself. He directed films such as "Philadelphia" in 1993, the 2004 remake of "The Manchurian Candidate.