Oprah Winfrey and director Ava DuVernay attend a special screening of "Selma" on Jan. 18, 2015, in Selma, Alabama. Oprah Winfrey will grace the big screen again on Disney's upcoming "A Wrinkle in Time." The media mogul will reunite with director Ava Duvernay, reports Variety. The two worked together on "Selma," with Duvernay in the director's chair and Winfrey playing a civil rights activist. The film will be an adaptation of Madeleine L'Engle's classic children's science-fiction book.