Geena Davis The Oscar winner returns to the big screen after a multiple-episode arc on ABC's 'Grey's Anatomy.' Thelma and Louise star Geena Davis has boarded the indie comedy Don't Talk to Irene. The casting marks Davis' return to the big screen after her Golden Globe-winning role as the president on ABC's Commander in Chief and a multiple-episode arc on Grey's Anatomy. With a passion for cheerleading, Irene secretly signs up the senior residents to audition for a dance-themed reality show to prove that you don?t need to be physically perfect to be awesome.