The dramatic comedy revolves around an improv group. Written and directed by Mike Birbiglia, who also co-stars and is producing, Don't Think Twice revolves around an improv group that loses its lease on its home theater at the same time that one of its castmembers gets chosen for the biggest sketch-comedy show on TV. The film delves into the bitterness and backstabbing that occur between friends when they realize that maybe not everyone?s going to make it after all.