VIDEO : Giuliana Rancic Reveals She and Husband Bill Rancic Lost Their Last Embryo

Giuliana Rancic and her husband, Bill Rancic , have always been open about their struggles with fertility, but now the E! News co-anchor reveals to People magazine that they have lost their final embryo. Giuliana and Bill were hoping to give their firstborn a sibling, something that just became that much harder due to their tragic lost. The couple learned on New Year's Eve that their surrogate, who was pregnant with their third and final embryo?had miscarried. After a surrogate gave birth to Duke in 2012, the couple had three embryos left and successfully implanted two into their surrogate.??